Aims To demonstrate the feasibility of complete primary surgical rehabilitation with simultaneous dental implant placement in the reconstructed jaw in oncologic patients, based on the experience of the N.N. Blokhin National Medical Research Center of Oncology (Moscow, Russia). Methodology Since November 2024, the Department of Head and Neck and Reconstructive Surgery has adopted a strategy of immediate dental implant placement in patients undergoing surgery for head and neck cancer. A total of 30 patients with oral cancer, cT3-4N0/+ disease, aged 25-65 years, ECOG 0-1, underwent ablative surgery with simultaneous mandibular or maxillary reconstruction with a fibular flap and immediate dental implant (DI) placement. A total of 89 implants were placed. The analysis included postoperative course, DI-related complications, and osseointegration was evaluated no earlier than 6 months after surgery according to Albrektsson failure criteria. Results Four implants were lost because of failed osseointegration or removal, resulting in an overall implant survival rate of 95.5%. Postoperative complications (neck wound infection, partial skin paddle necrosis, donor leg tendon exposure etc.) developed in 8 patients and were not related to DI placement. No necrosis of the revascularized flap occurred. Early rehabilitation, including return to oral feeding and decannulation on average by 10-14 days postoperatively. All patients started adjuvant RT/CRT within the standard time frame of 4-5 weeks after surgery. Conclusion This approach enabled restoration of jaw continuity and creation of the structural basis for subsequent prosthetic rehabilitation without separating reconstruction from the primary oncologic treatment course. The experience of a tertiary cancer center suggests that this strategy is feasible, reproducible, and clinically promising as part of routine multidisciplinary cancer care in appropriately selected patients.