Aims Oral cancer is a serious and deforming disease associated with multiple risk factors and high mortality rates especially among elderly population. This cross-sectional study was conducted to assess current knowledge, awareness about oral cancer risk factors and early signs among the rural and remote communities in Far North Queensland, Australia. Methodology After Bayesian disease mapping, the hotspots were identified with highest number of mortality rates and incidence rates. Cairns and Mackay regions were selected for conducting questionnaire survey and one-on-one interviews. To keep the sample size consistent and effective 150 participants were selected from both the locations. Ethics approvals were obtained from JCU HREC and Queensland HREC, along with SSA for Mackay site. Principal investigator was present onsite while the questionnaire was filled. Information sheet and consent forms were signed before survey. One-on-one interviews were conducted on 8 participants who volunteered to participate. Results The study revealed that 32% of Cairns participants were aware of oral cancer risk factors, whereas only 16% of Mackey participants were aware of oral cancer risk factors and Pre Malignant Diseases. The disparity in the level of awareness was assessed based on further investigation through interviews. High proportion of respondents agreed strongly that lack of awareness about oral cancer risk factors and the early signs of oral cancer which are the main cause of patients presenting late with advanced stage of the disease. Conclusion This study revealed that there is a significant lack of awareness about oral cancer risk factors and early symptoms. Improving awareness is crucial in implementing early intervention and prevention strategies. These measures will lead to decreased mortality rates especially in vulnerable elderly population.